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Cambridge International Science Publishing
MOLECULAR IMAGING THROUGH MAGNETIC RESONANCE FOR
CLINICAL ONCOLOGY
Karen
Belkic
Department of Oncology - Pathology Karolinska
Institute, Sweden
Institute for Health Promotion and Disease Prevention
Research, University of Southern California, USA |
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ISBN 1-904602-29-0
320
pages
240×160mm
Hardback
October 2004
£50/$85
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p&p
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Molecular
imaging is impacting dramatically upon virtually all areas of clinical
medicine. This is particularly true for oncology, where there is a growing
appreciation of the possibilities offered for early detection, by identifying
key changes for the emergence and progression of cancer on the molecular and/or
cellular level. Among the potentially most promising of these functional
imaging modalities are Magnetic Resonance Spectroscopy (MRS) and Spectroscopic
Imaging (MRSI) that involve the in vivo application of traditional
laboratory-based Nuclear Magnetic Resonance (NMR) techniques, and provide, in
addition to the anatomic picture, complementary biochemical and physiologic
information in the form of spectra. MRS and MRSI should be able to identify key
biochemical changes, much before the tumor becomes detectable by other
functional imaging methods that mainly rely upon single markers that are not
entirely sensitive or specific for malignant activity. Molecular imaging
through magnetic resonance could be potentially suited for screening and
repeated monitoring since it entails no exposure to ionizing radiation. Modern
systems now often have localization capabilities that can connect imaging to
spectroscopy.
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